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Keywords: Burkholderia pseudomallei
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Articles
Inhibition of d-glycero-β-d-manno-heptose 1-phosphate adenylyltransferase from Burkholderia pseudomallei by epigallocatechin gallate and myricetin
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (1): 235–245.
Published: 15 January 2021
...Suwon Kim; Seri Jo; Mi-Sun Kim; Heejin Kam; Dong Hae Shin Flavonoids play beneficial roles in various human diseases. In this study, a flavonoid library was employed to probe inhibitors of d - glycero -β- d - manno -heptose-1-phosphate adenylyltransferase from Burkholderia pseudomallei (Bp HldC...
Includes: Supplementary data
Articles
Aaron Butt, Victoria A. Higman, Christopher Williams, Matthew P. Crump, Claudia M. Hemsley, Nicholas Harmer, Richard W. Titball
Journal:
Biochemical Journal
Biochem J (2014) 459 (2): 333–344.
Published: 28 March 2014
... involvement in chronic and recurrent disease. We show that overexpression of the Burkholderia pseudomallei HicA toxin causes growth arrest and increases the number of persister cells tolerant to ciprofloxacin or ceftazidime. Furthermore, our data show that persistence towards ciprofloxacin or ceftazidime can...
Includes: Supplementary data
Articles
The structure of a Burkholderia pseudomallei immunophilin–inhibitor complex reveals new approaches to antimicrobial development
Available to PurchaseIsobel H. Norville, Katherine O'Shea, Mitali Sarkar-Tyson, Suxin Zheng, Richard W. Titball, Gabriele Varani, Nicholas J. Harmer
Journal:
Biochemical Journal
Biochem J (2011) 437 (3): 413–422.
Published: 13 July 2011
... isomerase activity and are inhibited by drugs including rapamycin and tacrolimus. We determined the structure of the Mip homologue [BpML1 ( Burkholderia pseudomallei Mip-like protein 1)] from the human pathogen and biowarfare threat B. pseudomallei by NMR and X-ray crystallography. The crystal structure...
Includes: Supplementary data
