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Keywords: CD44
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Biochem J (2008) 411 (2): 433–439.
Published: 27 March 2008
... as ‘shedding’. Among the major targets of ADAM10 are Notch, EphrinA2 and CD44. In many cell-based studies of shedding, the activity of ADAM10 appears to overlap with that of ADAM17, which has a similar active-site topology relative to the other proteolytically active ADAMs. The tissue inhibitors...
Biochem J (1999) 343 (1): 71–75.
Published: 24 September 1999
...Hans-Joachim LüKE; Peter PREHM The regulation of hyaluronan synthesis and shedding was analysed in human fibroblasts and in two melanoma cells that differed in the metastatic potential and proteolysis of the hyaluronan receptor CD44. Dissociation of nascent hyaluronan from plasma membranes isolated...