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Keywords: CFTR
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Biochem J (2021) 478 (10): 1891–1906.
Published: 24 May 2021
..., that is ablated by the β-blocker Propranolol and is absent from homozygous ΔF508-CFTR mice lacking functional CFTR. These data suggest that PDE4 acts within salivary glands to gate saliva secretion that is contingent upon the cAMP/PKA-dependent activation of CFTR. Indeed, PDE4 contributes the majority of total...
Includes: Supplementary data
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