...Giorgio Cozza; Sofia Zanin; Stefania Sarno; Elena Costa; Cristina Girardi; Giovanni Ribaudo; Mauro Salvi; Giuseppe Zagotto; Maria Ruzzene; Lorenzo A. Pinna By derivatizing the purely competitive CK2 inhibitor N 1-(4,5,6,7-tetrabromo-1 H -benzimidazol-2-yl)-propane-1,3-diamine (K137) at its 3-amino...

... further identified the protein kinase CK2 as the protein kinase for Sds3 Thr 49 and demonstrated that the protein kinase activity of CK2 is required for proper cell-cycle progression. Analysis of CK2 mutant mice reveals perturbation of skeletal muscle regeneration due to the dysregulation of cell-cycle...

...-binding domains of other partners of eIF2. In contrast, the N-terminus of ABC50 cannot bind to ribosomes by itself, but it can in conjunction with one of the nucleotide-binding domains. We demonstrate that ABC50 is a phosphoprotein and is phosphorylated at two sites by CK2. These sites, Ser-109 and Ser...

..., is phosphorylated by protein kinase CK2. The authors found that phosphorylation of this site is suppressed during interphase due to competing dephosphorylation by protein phosphatase 2A. Interestingly, protein phosphatase 2A is excluded from the nucleus during early mitosis, allowing CK2 to phosphorylate...

[email protected] ). 27 9 2001 2 1 2002 19 3 2002 The Biochemical Society, London ©2002 2002 casein CK2 protein phosphorylation Saccharomyces cerevisiae Ser/Thr kinase Abbreviations used: PKA, cAMP-dependent protein kinase; FSBA, fluorylsulphonylbenzoyladenosine...