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Keywords: CMG helicase
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Articles
Reconstitution of human CMG helicase ubiquitylation by CUL2 LRR1 and multiple E2 enzymes
Open Access
Journal:
Biochemical Journal
Biochem J (2021) 478 (14): 2825–2842.
Published: 23 July 2021
...Thanh Thi Le; Johanna Ainsworth; Cristian Polo Rivera; Thomas Macartney; Karim P.M. Labib Cullin ubiquitin ligases drive replisome disassembly during DNA replication termination. In worm, frog and mouse cells, CUL2 LRR1 is required to ubiquitylate the MCM7 subunit of the CMG helicase. Here, we show...
Includes: Supplementary data
