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1-2 of 2
Keywords: CTGF
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Articles
The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFβ1 responses in human proximal-tubule epithelial cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2006) 393 (2): 601–607.
Published: 23 December 2005
... an important role in the development of renal tubulo-interstitial fibrosis. Secretion of CTGF (connective-tissue growth factor; CCN2) by PTECs (proximal-tubule epithelial cells) and EMT (epithelial–mesenchymal transdifferentiation) of PTECs to myofibroblasts in response to TGFβ are critical Smad-dependent...
Articles
Uptake and intracellular transport of the connective tissue growth factor: a potential mode of action
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2001) 359 (1): 89–97.
Published: 24 September 2001
...Nadia Abdel WAHAB; Heike BRINKMAN; Roger M. MASON Connective tissue growth factor (CTGF) is a secreted cysteine-rich protein now considered as an important effector molecule in both physiological and pathological processes. An increasing amount of evidence indicates that CTGF plays a key role...
