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Keywords: Clock
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Articles

CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor α ( PPAR α) in mice

Katsutaka OISHI, Hidenori SHIRAI, Norio ISHIDA
Journal: Biochemical Journal
Biochem J (2005) 386 (3): 575–581.
https://doi.org/10.1042/BJ20041150
Published: 08 March 2005
... that circadian expression of mouse PPARα mRNA requires the basic helix–loop–helix PAS (Per-Arnt-Sim) protein CLOCK, a core component of the negative-feedback loop that drives circadian oscillators in mammals. The circadian expression of PPARα mRNA was abolished in the liver of homozygous Clock mutant mice. Using...
View articletitled, CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor α ( PPAR α) in mice
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Includes: Supplementary data
Articles

DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1

Yuxin LI, Xiulong SONG, Yuzhong MA, Jirong LIU, Dongfang YANG, Bingfang YAN
Journal: Biochemical Journal
Biochem J (2004) 382 (3): 895–904.
https://doi.org/10.1042/BJ20040592
Published: 07 September 2004
...Yuxin LI; Xiulong SONG; Yuzhong MA; Jirong LIU; Dongfang YANG; Bingfang YAN DEC1 (differentially expressed in chondrocytes 1) and DEC2 are E-box-binding transcription factors and exhibit a circadian expression pattern. Recently, both proteins were found to repress the Clock/Bmal1-activated E-box...
View articletitled, DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1
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Articles

Expression of the gene for Dec2, a basic helix–loop–helix transcription factor, is regulated by a molecular clock system

Hidenori HAMAGUCHI, Katsumi FUJIMOTO, Takeshi KAWAMOTO, Mitsuhide NOSHIRO, Koji MAEMURA, Norihiko TAKEDA, Ryozo NAGAI, Masae FURUKAWA, Sato HONMA, Ken-ichi HONMA, Hidemi KURIHARA, Yukio KATO
Journal: Biochemical Journal
Biochem J (2004) 382 (1): 43–50.
https://doi.org/10.1042/BJ20031760
Published: 10 August 2004
... for the clockwork system. Transcripts of Dec2 , as well as those of its related gene Dec1 , exhibit a striking circadian oscillation in the suprachiasmatic nucleus, and Dec2 inhibits transcription from the Per1 promoter induced by Clock/Bmal1 [Honma, Kawamoto, Takagi, Fujimoto, Sato, Noshiro, Kato and Honma (2002...
View articletitled, Expression of the gene for Dec2, a basic helix–loop–helix transcription factor, is regulated by a molecular clock system
Open the PDF for Expression of the gene for Dec2, a basic helix–loop–helix transcription factor, is regulated by a molecular clock system in another window