...Sheng-He Huang; Chu-Hua Wu; Shibo Jiang; Ingrid Bahner; Albert S. Lossinsky; Ambrose Y. Jong Cryptococcus neoformans causes life-threatening meningoencephalitis, particularly prevalent in AIDS patients. The interrelationship between C. neoformans and HIV-1 is intriguing, as both pathogens elicit...

...Julianne T. Djordjevic; Maurizio Del Poeta; Tania C. Sorrell; Kylie M. Turner; Lesley C. Wright The secreted, multifunctional enzyme PLB1 (phospholipase B1 protein encoded by the PLB1 gene) is a virulence determinant of the pathogenic fungus Cryptococcus neoformans , but the mechanism of its...

...Daniel AGRANOFF; Lauren COLLINS; David KEHRES; Tom HARRISON; Michael MAGUIRE; Sanjeev KRISHNA Cryptococcus neoformans is an important human opportunistic pathogen and a facultative intracellular parasite, particularly in HIV-infected individuals. Little is known about metal ion transport...

... Cryptococcus neoformans . In this fungus, UDP-GlcA is required for the synthesis of capsule polysaccharides, which in turn are essential for virulence. The gene was expressed in Escherichia coli and the 51.3-kDa recombinant protein from wild-type and five mutants was purified for analysis. The cryptococcal...

... activity [Bobek and Situ (2003) Antimicrob. Agents Chemother. 47 , 645–652]. The aims of the present study were to determine the minimum peptide chain length and its location within the 20-mer region that retains potent antifungal activity against Candida albicans and Cryptococcus neoformans and to examine...