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Keywords: DNA-encoded library
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Articles
Methods to accelerate PROTAC drug discovery
Open Access
Journal:
Biochemical Journal
Biochem J (2025) 482 (13): 921–937.
Published: 25 June 2025
... without the need for extensive purification [ 54 ]. Both parallel chemistry and SPOS have been shown to be suitable for combinatorial strategies to generate libraries of PROTAC analogues. Thirdly, DNA-encoded library (DEL) technologies, which enable the synthesis and screening of vast compound libraries...
