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Keywords: Dicer
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Articles
Biochem J (2014) 462 (2): 347–358.
Published: 07 August 2014
... replication of viruses in plant, invertebrate and vertebrate systems. However, comparatively little is known about the interplay between RNAi and various viral infections in mammalian hosts. We show in the present study that the siRNA-mediated silencing of Drosha , Dicer and Ago2 [argonaute RISC (RNA-induced...
Articles
Biochem J (2008) 412 (3): 527–534.
Published: 28 May 2008
... to acute stress or harmful agents has not been extensively investigated. Here, we have studied the role of Dicer, one of the central proteins of the miRNA processing machinery during apoptosis, and show that down-regulation of Dicer results in accelerated apoptosis of HeLa cells, triggered by TNFα...
Articles
Biochem J (2008) 410 (1): 39–48.
Published: 29 January 2008
... previously [ 33 ]. Oligodeoxynucleotide transcription templates and mutagenic oligonucleotides were synthesized by Invitrogen, and the deprotected DNAs were purified by denaturing gel electrophoresis [ 28 ]. Purified DNAs were stored at −80 °C in 10 mM Tris/HCl and 1 mM EDTA (pH 8). Dicer double...
Articles
Biochem J (2005) 387 (3): 561–571.
Published: 26 April 2005
...Katarzyna JARONCZYK; Jon B. CARMICHAEL; Tom C. HOBMAN PPD (PAZ Piwi domain) proteins and the Dicer family have been the subjects of intense study over the last 6 years. These proteins have well-established roles in RNAi (RNA interference), a process that relies on siRNAs (small interfering RNAs) or...