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Keywords: Dictyostelium discoideum
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Biochem J (2018) 475 (3): 643–648.
Published: 14 February 2018
...) . Dictyostelium discoideum macropinocytosis PIP3 protein kinase B Ras One of the most rapid and dramatic effects of growth factors on responsive cells is to stimulate their actin cytoskeleton into a brief period of ruffling and macropinocytosis [ 1 ]. This can be mimicked with oncogenic Ras [ 2 ] and...
Biochem J (2014) 459 (2): 241–249.
Published: 28 March 2014
...Gong Chen; Xiaoqun Xu; Xiangfu Wu; Alexander Thomson; Chi-Hung Siu In Dictyostelium discoideum , TgrB1 and TgrC1 are partners of a heterophilic cell-adhesion system. To investigate its assembly process, the split GFP complementation assay was used to track the oligomeric status of both proteins...
Includes: Supplementary data
Biochem J (2013) 452 (2): 259–269.
Published: 10 May 2013
...Gong Chen; Jun Wang; Xiaoqun Xu; Xiangfu Wu; Ruihan Piao; Chi-Hung Siu Cell–cell adhesion plays crucial roles in cell differentiation and morphogenesis during development of Dictyostelium discoideum . The heterophilic adhesion protein TgrC1 (Tgr is transmembrane, IPT, IG, E-set, repeat protein) is...
Includes: Supplementary data
Biochem J (2012) 447 (3): 353–361.
Published: 05 October 2012
... diphosphate synthase). NBPs inhibit also growth of amoebae of Dictyostelium discoideum in which their target is again FDPS. A fusion protein between FDPS and GFP (green fluorescent protein) was found, in D. discoideum , to localize to peroxisomes and to confer resistance to the NBP alendronate. GFP was also...
Biochem J (2009) 423 (1): 41–52.
Published: 14 September 2009
...Birgit Schiller; Alba Hykollari; Josef Voglmeir; Gerald Pöltl; Karin Hummel; Ebrahim Razzazi-Fazeli; Rudolf Geyer; Iain B. H. Wilson The social amoeba Dictyostelium discoideum has become established as a simple model for the examination of cell–cell interactions, and early studies suggested that...
Includes: Supplementary data
Biochem J (2007) 402 (1): 153–161.
Published: 25 January 2007
...Sonya Bader; Arjan Kortholt; Peter J. M. Van Haastert The Dictyostelium discoideum genome uncovers seven cyclic nucleotide PDEs (phosphodiesterases), of which six have been characterized previously and the seventh is characterized in the present paper. Three enzymes belong to the ubiquitous class I...
Biochem J (2007) 401 (1): 309–316.
Published: 11 December 2006
...Elisa Alvarez-Curto; Karin E. Weening; Pauline Schaap Intracellular and secreted cAMPs play crucial roles in controlling cell movement and gene regulation throughout development of the social amoeba Dictyostelium discoideum . cAMP is produced by three structurally distinct ACs (adenylate cyclases...
Biochem J (2003) 376 (2): 473–479.
Published: 01 December 2003
... the CDase cDNA, consisting of 2142 nucleotides encoding 714 amino-acid residues, from the slime mould, Dictyostelium discoideum . The putative amino-acid sequence indicates 32–42% identity with various neutral CDases, but does not show any similarity to the acid and alkaline CDases, indicating the...
Biochem J (2003) 374 (3): 697–705.
Published: 15 September 2003
...Marc A. DE LA ROCHE; Sheu-Fen LEE; Graham P. CÔTÉ Dictyostelium discoideum MyoD, a long-tailed class I myosin, co-purified with two copies of a 16 kDa light chain. Sequence analysis of the MyoD light chain showed it to be a unique protein, termed MlcD, that shares 44% sequence identity with...