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Keywords: G1 arrest
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Articles
Iron chelation-induced senescence-like growth arrest in hepatocyte cell lines: association of transforming growth factor β1 (TGF-β1)-mediated p27Kip1 expression
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2002) 366 (2): 613–621.
Published: 01 September 2002
..., implying their roles as major mediators in the senescent process. To test this possibility, the expression of p53 was Figure 3 G1 arrest by DFO mediated through induction of p27 Kip1, but not of p21Cip1 Time-dependent expression of p53 and CDKIs, including p15INK4b (p15), p16INK4a (p16), p21Cip1 (p21...
Articles
Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts
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Journal:
Biochemical Journal
Biochem J (2000) 347 (2): 543–551.
Published: 10 April 2000
.... Apoptotic cells were mainly distributed in the S-phase of the cell cycle, while growth-arrested cells exhibited predominantly G1- and G2/M-phase distributions. H 2 O 2 pretreatment induced G1 arrest and prohibited induction of apoptosis by a subsequent H 2 O 2 challenge. The p53 protein showed an average...
