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Keywords: GSK-3β (glycogen synthase kinase-3β)
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Articles
Transforming growth factor-β2 promotes Snail-mediated endothelial–mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling
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Journal:
Biochemical Journal
Biochem J (2011) 437 (3): 515–520.
Published: 13 July 2011
... to cause EndMT. Chemical inhibition of GSK-3β (glycogen synthase kinase-3β) allows EndMT to be induced by Snail overexpression. Expression of a mutant Snail protein that is resistant to GSK-3β-dependent inactivation also promotes EndMT. These results provide the foundation for understanding the roles...
