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Keywords: Hsp27
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Journal:
Biochemical Journal
Biochem J (2025) 482 (09): 413–432.
Published: 25 April 2025
... αB-crystallin (αB-c; HSPB5) and Hsp27 (HSPB1). We show that small (monomeric or dimeric) forms of both αB-c and Hsp27 bind to misfolded or oligomeric forms of the client proteins at early stages of aggregation, resulting in the formation of soluble sHsp–client complexes. Stoichiometric analysis...
Includes: Supplementary data