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1-38 of 38
Keywords: Hydrogen Peroxide
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Articles
Jonathan Chevriau, Gerardo Zerbetto De Palma, Cintia Jozefkowicz, Victoria Vitali, Agustina Canessa Fortuna, Nicolas Ayub, Gabriela Soto, Gerd Patrick Bienert, Ari Zeida, Karina Alleva
Journal:
Biochemical Journal
Biochem J (2024) 481 (19): 1329–1347.
Published: 25 September 2024
...Jonathan Chevriau; Gerardo Zerbetto De Palma; Cintia Jozefkowicz; Victoria Vitali; Agustina Canessa Fortuna; Nicolas Ayub; Gabriela Soto; Gerd Patrick Bienert; Ari Zeida; Karina Alleva Hydrogen peroxide (H 2 O 2 ) transport by aquaporins (AQP) is a critical feature for cellular redox signaling...
Includes: Supplementary data
Articles
Salvador González-Gordo, Javier López-Jaramillo, Marta Rodríguez-Ruiz, Jorge Taboada, José M. Palma, Francisco J. Corpas
Journal:
Biochemical Journal
Biochem J (2024) 481 (13): 883–901.
Published: 03 July 2024
.... Statistically significant changes in expression levels ( P < 0.05) compared with green fruit (G) are indicated with diamonds. catalase fruit ripening hydrogen peroxide nitration nitric oxide The time-course expression analyses by RNAseq of the three CaCAT genes throughout fruit ripening...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2019) 476 (12): 1781–1790.
Published: 26 June 2019
... modulation by using hydrogen peroxide (H 2 O 2 ) as an oxidizing force. This system plays a key role in switching chloroplast metabolism (e.g. Calvin–Benson cycle) during light to dark transitions; however, information on its function is still limited. In this study, we report a novel protein-activation...
Includes: Supplementary data
Articles
In Collection
Photosynthesis
Journal:
Biochemical Journal
Biochem J (2019) 476 (10): 1539–1551.
Published: 31 May 2019
... that the half-saturation concentration of G6PDH isoform 1 is increased under reducing conditions. The other two isoforms exhibit less redox regulation, however, isoform 2 is strongly inhibited by NADPH. Redox regulation of G6PDH1 can be partially reversed by hydrogen peroxide or protected against...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2018) 475 (19): 3153–3169.
Published: 12 October 2018
... and cytotoxicity revealed differences between the assessed α-syn species. Only oligomers induced mitochondrial dysfunction in astrocytes and significantly increased extracellular hydrogen peroxide production by these cells. Besides, TNF-α and IL-1β (interleukin 1β) expression presented different kinetics...
Includes: Supplementary data
Articles
Adam Neal, Austin Rountree, Kelly Kernan, Brian Van Yserloo, Huiliang Zhang, Benjamin J. Reed, William Osborne, Wang Wang, Ian R. Sweet
Journal:
Biochemical Journal
Biochem J (2016) 473 (23): 4443–4456.
Published: 25 November 2016
...Adam Neal; Austin Rountree; Kelly Kernan; Brian Van Yserloo; Huiliang Zhang; Benjamin J. Reed; William Osborne; Wang Wang; Ian R. Sweet A real-time method to measure intracellular hydrogen peroxide (H 2 O 2 ) would be very impactful in characterizing rapid changes that occur in physiologic...
Includes: Supplementary data
Articles
Rebecca A. Poynton, Alexander V. Peskin, Alexina C. Haynes, W. Todd Lowther, Mark B. Hampton, Christine C. Winterbourn
Journal:
Biochemical Journal
Biochem J (2016) 473 (4): 411–421.
Published: 09 February 2016
... to hyperoxidation is partly explained by differences in four C-terminal amino acids. In addition, only one active-site cysteine in the Prx3 homodimer is susceptible to hyperoxidation whereas both become hyperoxidized in Prx2. hydrogen peroxide kinetics peroxiredoxin inactivation thiol antioxidants...
Articles
Abdel A. Belaidi, Juliane Röper, Sita Arjune, Sabina Krizowski, Aleksandra Trifunovic, Guenter Schwarz
Journal:
Biochemical Journal
Biochem J (2015) 469 (2): 211–221.
Published: 06 July 2015
... that determine the reactivity of PSO towards oxygen, remained unknown. In the present study, we generated mammalian haem-deficient and truncated SO variants and demonstrated their oxygen reactivity by hydrogen peroxide formation and oxygen-consumption studies. We found that intramolecular electron transfer...
Includes: Supplementary data
Articles
Taek-Keun Kim, Joo Hyun Nam, Won-Gyun Ahn, Nam-Ho Kim, Hwa-Yong Ham, Chang-Won Hong, Ju-Suk Nam, Jongho Lee, Sung-Oh Huh, Insuk So, Sung Joon Kim, Dong-Keun Song
Journal:
Biochemical Journal
Biochem J (2013) 455 (3): 319–327.
Published: 10 October 2013
... compilation © 2013 Biochemical Society 2013 Point-mutation study revealed that Lys 1110 is critical for TRPM2 (transient receptor potential melastatin 2) channel activation. adenosine diphosphoribose (ADPR) chloride hydrogen peroxide positive charge point mutation Changes in free...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2013) 453 (3): 475–485.
Published: 12 July 2013
... on the hyperoxidized status of a Prx. 1 To whom correspondence should be addressed (email [email protected] ). 4 1 2013 23 5 2013 28 5 2013 28 5 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 hydrogen peroxide hyperoxidation...
Includes: Supplementary data
Articles
Leticia P. Roma, Jessica Duprez, Hilton K. Takahashi, Patrick Gilon, Andreas Wiederkehr, Jean-Christophe Jonas
Journal:
Biochemical Journal
Biochem J (2012) 441 (3): 971–978.
Published: 16 January 2012
... changes in mitochondrial hydrogen peroxide concentration and glutathione redox state in adenovirus-infected rat islet cell clusters. Because of the reported pH sensitivity of HyPer, the results were compared with those obtained with the mitochondrial pH sensors mt-AlpHi and mt-SypHer. The fluorescence...
Articles
Journal:
Biochemical Journal
Biochem J (2010) 425 (2): 313–325.
Published: 23 December 2009
... to inactivation by hyperoxidation in the presence of excess peroxide and the ability to form complex oligomeric structures. These properties, combined with a high cellular abundance and reactivity with hydrogen peroxide, have led to speculation that the Prxs function as redox sensors that transmit signals as part...
Articles
Oxidation of methionine residues: the missing link between stress and signalling responses in plants
Journal:
Biochemical Journal
Biochem J (2009) 422 (2): e1–e2.
Published: 13 August 2009
... 17 1866 1875 2 Neill S. J. Desikan R. Clarke A. Hurst R. D. Hancock J. T. Hydrogen peroxide and nitric oxide as signalling molecules in plants J. Exp. Bot. 2002 53 1237 1247 3 Lamb C. Dixon R. A. The oxidative burst in plant disease resistance...
Articles
Andrew G. Cox, Andree G. Pearson, Juliet M. Pullar, Thomas J. Jönsson, W. Todd Lowther, Christine C. Winterbourn, Mark B. Hampton
Journal:
Biochemical Journal
Biochem J (2009) 421 (1): 51–58.
Published: 12 June 2009
...Andrew G. Cox; Andree G. Pearson; Juliet M. Pullar; Thomas J. Jönsson; W. Todd Lowther; Christine C. Winterbourn; Mark B. Hampton The Prxs (peroxiredoxins) are a family of cysteine-dependent peroxidases that decompose hydrogen peroxide. Prxs become hyperoxidized when a sulfenic acid formed during...
Includes: Multimedia, Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2009) 417 (1): 1–13.
Published: 12 December 2008
...://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. complex I hydrogen peroxide mitochondrion reactive oxygen species (ROS) respiratory chain superoxide Mitochondria...
Includes: Multimedia, Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2008) 414 (1): 53–61.
Published: 29 July 2008
..., U.S.A. 4 To whom correspondence should be addressed (email [email protected] ). 1 2 2008 6 5 2008 8 5 2008 8 5 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 aquaglyceroporins aquaporin hydrogen peroxide reactive...
Includes: Supplementary data
Articles
Lena Serrander, Laetitia Cartier, Karen Bedard, Botond Banfi, Bernard Lardy, Olivier Plastre, Andrzej Sienkiewicz, Lászlo Fórró, Werner Schlegel, Karl-Heinz Krause
Journal:
Biochemical Journal
Biochem J (2007) 406 (1): 105–114.
Published: 26 July 2007
... induced with 1 μg/ml tet, TC). The dose–response curve was fitted with a four-parameter Hill sigmoid curve for the determination of the EC 50 ( n =4). hydrogen peroxide NADPH oxidase (NOX) NOX4 NOX4 inhibitor reactive oxygen species (ROS) superoxide NOX4 is a member of the NOX (NADPH...
Articles
Journal:
Biochemical Journal
Biochem J (2007) 405 (1): 51–59.
Published: 13 June 2007
... . 1 To whom correspondence should be addressed (email [email protected] ). 4 8 2006 14 2 2007 27 2 2007 27 2 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 brain calcineurin hydrogen peroxide iron superoxide dismutase zinc Cn...
Articles
Journal:
Biochemical Journal
Biochem J (2006) 394 (3): 707–713.
Published: 24 February 2006
...Christine J. van Dalen; Christine C. Winterbourn; Anthony J. Kettle Eosinophil peroxidase is a haem enzyme of eosinophils that is implicated in oxidative tissue injury in asthma. It uses hydrogen peroxide to oxidize thiocyanate and bromide to their respective hypohalous acids. Nitrite is also...
Articles
Pedro IÑARREA, Hadi MOINI, Daniel RETTORI, Derick HAN, Jesús MARTÍNEZ, Inés GARCÍA, Erika FERNÁNDEZ-VIZARRA, María ITURRALDE, Enrique CADENAS
Journal:
Biochemical Journal
Biochem J (2005) 387 (1): 203–209.
Published: 22 March 2005
... containing 0.1 mM DETAPAC (diethylenetriaminepenta-acetic acid) and was purified several times with activated charcoal; DMPO concentration was calculated spectrophotometrically (ε 232 =7700 M −1 ·cm −1 ); the stock solution was kept under helium at −20 °C. Cu,Zn-superoxide dismutase hydrogen peroxide...
Articles
Journal:
Biochemical Journal
Biochem J (2005) 385 (3): 763–768.
Published: 24 January 2005
... of tightly bound NADPH. 1 To whom correspondence should be addressed (email [email protected] ). 2 9 2004 22 9 2004 29 9 2004 29 9 2004 The Biochemical Society, London 2005 catalase glucose-6-phosphate dehydrogenase hydrogen peroxide NADH NADPH oxidative...
Articles
Journal:
Biochemical Journal
Biochem J (2004) 378 (3): 1039–1045.
Published: 15 March 2004
... Society, London ©2004 2004 DNA damage hydrogen peroxide lysosomal iron lysosome oxidative stress telomere Abbreviations used: AO, Acridine Orange; DFO, desferrioxamine; FADU, fluorescence-detected alkaline DNA unwinding; HMM-DFO, high-molecular-mass DFO; MSDH, O -methyl-serine...
Articles
Journal:
Biochemical Journal
Biochem J (2003) 371 (3): 877–885.
Published: 01 May 2003
.... These results demonstrate that activation of the HO-1 gene by glucose deprivation is mediated by a glucose metabolic response pathway via generation of ROS and that the pathway requires a functional electron-transport chain. Key words: antioxidant, hydrogen peroxide, mitochondrial respiration, oxidant stress...
Articles
Journal:
Biochemical Journal
Biochem J (2002) 361 (3): 681–688.
Published: 25 January 2002
... To whom correspondence should be addressed (e-mail [email protected] ). 4 10 2001 20 10 2001 19 11 2001 The Biochemical Society, London ©2002 2002 caveolae hydrogen peroxide post-translational modification Abbreviation used: ECs, endothelial cells. Biochem. J. (2002...
Articles
Natalia A. RIOBÓ, Emilio CLEMENTI, Mariana MELANI, Alberto BOVERIS, Enrique CADENAS, Salvador MONCADA, Juan J. PODEROSO
Journal:
Biochemical Journal
Biochem J (2001) 359 (1): 139–145.
Published: 24 September 2001
... anions, hydrogen peroxide and peroxynitrite, the latter shown by nitration of mitochondrial proteins. Long-term incubation of mitochondrial membranes with NO resulted in a persistent inhibition of NADH:cytochrome c reductase activity, interpreted as inhibition of NADH:ubiquinone reductase (Complex I...
Articles
Journal:
Biochemical Journal
Biochem J (2001) 358 (2): 335–342.
Published: 24 August 2001
.... In addition, methylamine-induced adipocyte maturation was mimicked by 3T3-L1 cell treatment with other SSAO substrates. Finally, the large reversion of methylamine action by catalase indicated that hydrogen peroxide generated by SSAO was involved, at least in part, in the modulation of adipocyte maturation...
Articles
Journal:
Biochemical Journal
Biochem J (2001) 357 (1): 241–247.
Published: 25 June 2001
...2001 2001 hydrogen peroxide iron iron storage proteins reactive oxygen species transfection Abbreviations used: CAT, chloramphenicol acetyltransferase; DCF, 2′,7′-dichlorofluorescein; DMEM, Dulbecco's modified Eagle's medium; DTT, dithiothreitol; FBS, fetal bovine serum; H 2 DCF-DA...
Articles
Journal:
Biochemical Journal
Biochem J (2001) 355 (3): 757–763.
Published: 24 April 2001
... and metabolic actions in both early and fully differentiated 3T3-L1 adipocytes. This emphasizes compart- ment-specific activation of PI 3-kinase as an oxidation-sensitive step specifically leading to insulin resistance. Key words: diabetes, hydrogen peroxide, insulin resistance, PI 3-kinase. consequently...
Articles
Journal:
Biochemical Journal
Biochem J (2001) 355 (3): 653–661.
Published: 24 April 2001
... ). 30 10 2000 18 1 2001 13 2 2001 The Biochemical Society, London © 2001 2001 calcium caspase-3 hydrogen peroxide hydroxyl radical superoxide radical anion Biochem. J. (2001) 355, 653 661 (Printed in Great Britain) 653 Reactive oxygen species involved in trichosanthin...
Articles
Journal:
Biochemical Journal
Biochem J (2001) 353 (2): 411–416.
Published: 08 January 2001
...Derick HAN; Everett WILLIAMS; Enrique CADENAS It has been generally accepted that superoxide anion generated by the mitochondrial respiratory transport chain are vectorially released into the mitochondrial matrix, where they are converted to hydrogen peroxide through the catalytic action of Mn...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 352 (2): 389–397.
Published: 24 November 2000
... activity, hydrogen peroxide, intracellular free Ca#+ concentration, mitochondrial membrane potential, reactive oxygen species. glucokinase inhibition is the oxidation of two adjacent thiol groups in the sugar-binding site of the enzyme [12]. Some authors have postulated that the alloxan effect is due...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 348 (3): 615–619.
Published: 07 June 2000
...-workers [17] have also demonstrated that enhanced bilirubin production following activation of haem oxygenase-2 (HO-2), the constitutive isoform of haem oxygenase, is protective against the neurotoxicity elicited by hydrogen peroxide [17]. However, further studies on the physiological importance...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 348 (3): 525–530.
Published: 07 June 2000
... in a Rac signalling pathway leading to the generation of ROS. hydrogen peroxide leukotrienes 5-lipoxygenase signal transduction Biochem. J. (2000) 348, 525 530 (Printed in Great Britain) 525 Involvement of cytosolic phospholipase A2, and the subsequent release of arachidonic acid, in signalling...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 348 (2): 425–432.
Published: 23 May 2000
... through cell-cycle arrest. 1 To whom correspondence should be addressed (e-mail joeman@;mailsrv.ym.edu.tw). 30 9 1999 8 3 2000 29 3 2000 The Biochemical Society, London © 2000 2000 aging cell-cycle arrest hydrogen peroxide mtDNA copy number reactive oxygen species...
Articles
Journal:
Biochemical Journal
Biochem J (2000) 348 (1): 235–240.
Published: 09 May 2000
..., hepatoma cells, hydrogen peroxide, redox regulation, transcription. collagen gene) and repressed by tumour necrosis factor a and oxidative stress (thus mediating the CYP1A1 gene inhibition) [4,7,8]. The last 13 residues of NFI}CTF were identified as the TGFb-responsive domain (TRD) [9]. In fibroblasts...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 344 (2): 359–366.
Published: 24 November 1999
... phosphorylation. In io, this mech- anism would lead to the sensitization of platelet activation and may be an important risk factor in thrombotic disease. Key words: arsenite, hydrogen peroxide, platelets, sorbitol, stress-activated protein kinase. activates platelets via a tyrosine-kinase dependent pathway...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 343 (1): 185–190.
Published: 24 September 1999
... model of the apoenzyme is proposed. Key words: EPR, germin, homology model, hydrogen peroxide. family which bind metal ions such as the Fe- or possibly Zn- containing phosphomannose isomerases and the Fe-containing dioxygenases [15]. A homology model of the barley enzyme indicates the clustering...
Articles
Peter KOTSONIS, Armin FREY, Lothar G. FRÖHLICH, Heinrich HOFMANN, Andreas REIF, David A. WINK, Martin FEELISCH, Harald H. H. W. SCHMIDT
Journal:
Biochemical Journal
Biochem J (1999) 340 (3): 745–752.
Published: 08 June 1999
... affecting enzyme activity. 1 To whom correspondence should be addressed (e-mail [email protected]). 5 1 1999 8 3 1999 20 3 1999 The Biochemical Society, London © 1999 1999 autoregulation hydrogen peroxide NOS catalysis Biochem. J. (1999) 340, 745 752...
