... pathway, including the mitogen-activated protein kinases (MAPKs) and the NF (nuclear factor)-κB signaling pathway, but its analog L-K5, which had the same amino acid sequence as L-K6 but no Lys residue at the –COOH terminal, only inhibited the phosphorylation of I-κB and NF-κB. Importantly, L-K6 and L-K5...

...), PI3K (phosphoinositide kinase)/Akt and MAPK (mitogen-activated protein kinase). Most of these insulin pathways are probably also active in the ovary and their ability to interact with each other and also with follicle-stimulating hormone (FSH) and luteinizing hormone (LH) signalling pathways enables...

...Kyle Bauckman; Edward Haller; Nicholas Taran; Stephanie Rockfield; Abigail Ruiz-Rivera; Meera Nanjundan The role of iron in the development of cancer remains unclear. We previously reported that iron reduces cell survival in a Ras/mitogen-activated protein kinase (MAPK)-dependent manner in ovarian...

...David PLOWS; Paraskevi BRIASSOULI; Carolyn OWEN; Vassilis ZOUMPOURLIS; Michelle D. GARRETT; Alexander PINTZAS The Ras family of GTP-binding proteins are key transducers of extracellular signals, particularly through the mitogen-activated protein kinase (MAPK) pathway. Constitutively active forms...

...Jeannie M. GRIPENTROG; Algirdas J. JESAITIS; Heini M. MIETTINEN The formyl peptide receptor (FPR) is a G-protein-coupled receptor (GPCR) that mediates chemotaxis and stimulates the mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinase pathway. We have examined the functional...

...Lindy ABAS; Marie A. BOGOYEVITCH; Michael GUPPY To search for the stimuli involved in activating the mitogen-activated protein kinases (MAPKs) during ischaemia and reperfusion, we simulated the event in a system in vitro conducive to continuous and non-invasive measurements of several major...

... phosphorylated tyrosines on the CSF-1R activate multiple cis -acting elements on the complex uPA promoter. 1 To whom correspondence should be addressed (e-mail D.Hume@;cmcb.uq.edu.au). 31 8 1999 22 11 1999 20 1 2000 The Biochemical Society, London © 2000 2000 c-Fms Ets MAPK...