.... The aim of the present review is to show the evolution of thought regarding the glyoxalase pathway since its discovery 100 years ago, the current knowledge on the glyoxalase enzymes and their recognized role in the control of glycation processes. glycation glyoxalase Maillard reaction methylglyoxal...

... 222 224 3 Monnier V. M. Mustata G. T. Biemel K. L. Reihl O. Lederer M. O. Zhenyu D. Sell D. R. Cross-linking of the extracellular matrix by the Maillard reaction in aging and diabetes: an update on “a puzzle nearing resolution” Ann. N. Y. Acad. Sci. 2005 1043...

...Vincent M. Monnier Deglycating enzymes, i.e. enzymes that reverse the initial stage of the Maillard reaction between glucose and primary amines, are known to occur in mammalian, fungal and other eukaryotic and prokaryotic cells. In this issue of Biochemical Journal , Wiame et al. now report...

...António E. N. FERREIRA; Ana M. J. PONCES FREIRE; Eberhard O. VOIT The Maillard reaction between reducing sugars and amino groups of biomolecules generates complex structures known as AGEs (advanced glycation endproducts). These have been linked to protein modifications found during aging, diabetes...

... is a major AGE in collagen. Key words: carboxymethylation, enzymatic hydrolysis, glucose, Maillard reaction. isolation and structure of the new glycation product from glycated collagen. EXPERIMENTAL Materials [1C]Glucose was purchased from Aldrich (Milwaukeee, WI, U.S.A Collagenase N-2 was from Nitta Gelatin...