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Keywords: NAD+
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Articles
Biochem J (2008) 411 (2): e11–e13.
Published: 27 March 2008
...William C. Hallows; Brittany N. Albaugh; John M. Denu Sirtuins are NAD + -dependent enzymes that have been implicated in a wide range of cellular processes, including pathways that affect diabetes, cancer, lifespan and Parkinson's disease. To understand their cellular function in these age-related...
Articles
Biochem J (2006) 395 (2): 417–426.
Published: 28 March 2006
...Claire Ceni; Nathalie Pochon; Michel Villaz; Hélène Muller-Steffner; Francis Schuber; Julie Baratier; Michel De Waard; Michel Ronjat; Marie-Jo Moutin cADPR (cADP-ribose), a metabolite of NAD + , is known to modulate intracellular calcium levels and to be involved in calcium-dependent processes...
Articles
Biochem J (2006) 393 (3): 697–704.
Published: 13 January 2006
...Santina Bruzzone; Iliana Moreschi; Lucrezia Guida; Cesare Usai; Elena Zocchi; Antonio De Flora β-NAD + e (extracellular β-NAD + ), present at nanomolar levels in human plasma, has been implicated in the regulation of [Ca 2+ ] i (the intracellular calcium concentration) in various cell types...
Articles
Biochem J (2005) 389 (3): 853–861.
Published: 26 July 2005
... 4 2005 21 4 2005 The Biochemical Society, London 2005 ADP-ribosyltransferase DT40 cell glycosylphosphatidylinositol (GPI) anchor NAD + Mono-ADP-ribosylation is a post-translational modification whereby a single ADP-ribose moiety of NAD + is transferred to the amino...
Articles
Biochem J (2004) 382 (3): E5.
Published: 07 September 2004
...Mathias ZIEGLER; Marc NIERE NAD + and its metabolites serve important functions in intracellular signalling. NAD + -mediated regulatory processes also take place on the cell surface, particularly of immune cells. In this issue of the Biochemical Journal , Gerth et al. have demonstrated a new...
Articles
Biochem J (2004) 382 (3): 849–856.
Published: 07 September 2004
...Anja GERTH; Karen NIEBER; Norman J. OPPENHEIMER; Sunna HAUSCHILDT Ca 2+ ions play a critical role in the biochemical cascade of signal transduction pathways, leading to the activation of immune cells. In the present study, we show that the exposure of freshly isolated human monocytes to NAD...
Articles
Biochem J (2003) 370 (1): 175–183.
Published: 15 February 2003
... NAD + -glycohydrolase activity, CD38 is also able to synthesize cyclic ADP-ribose, an endogenous calcium-regulating molecule, from NAD + . In the present study, we have compared ADP-ribosyl cyclase and NAD + -glycohydrolase activities in protein extracts of brains from developing and adult wild-type...
Articles
Biochem J (2002) 361 (2): 379–384.
Published: 08 January 2002
...Richard GRAEFF; Hon Cheung LEE cADP-ribose (cADPR) is a novel cyclic nucleotide derived from NAD + that has now been established as a general Ca 2+ messenger in a wide variety of cells. Despite the obvious importance of monitoring its cellular levels under various physiological conditions, its...
Articles
Biochem J (2000) 352 (1): 197–202.
Published: 07 November 2000
.... 1 To whom correspondence should be addressed (e-mail haruhiro@med.kanazawa-u.ac.jp ). 29 11 1999 22 8 2000 15 9 2000 The Biochemical Society, London © 2000 2000 ADP-ribosyl cyclase angiotensin II receptor NAD+ signal transduction ventricular muscle Biochem. J...
Articles
Biochem J (2000) 345 (1): 43–52.
Published: 17 December 1999
...Angélique AUGUSTIN; Hélène MULLER-STEFFNER; Francis SCHUBER Bovine spleen ecto-NAD + glycohydrolase, an archetypal member of the mammalian membrane-associated NAD(P) + glycohydrolase enzyme family (EC 3.2.2.6), displays catalytic features similar to those of CD38, i.e. a protein originally...