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Keywords: NADH oxidase
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Biochem J (2007) 405 (3): 559–568.
Published: 13 July 2007
... found that the first step is mediated in the plasma membrane by NADH oxidase, which rapidly generates ROS (reactive oxygen species). These ROS then directly stimulate MMPs (matrix metalloproteinases) and allow them to cleave and release Hb-EGF [heparin-binding EGF (epidermal growth factor...