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1-6 of 6
Keywords: Nrf2
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Articles
Paul G. Shiels, Johanna Painer, Barbara Natterson-Horowitz, Richard J. Johnson, Jaime J. Miranda, Peter Stenvinkel
Journal:
Biochemical Journal
Biochem J (2021) 478 (14): 2889–2898.
Published: 28 July 2021
... Attribution License 4.0 (CC BY-NC-ND) . ageing allostatic load biomimetics exposome microbiome Nrf2 There has been a slow response to adapt to a tsunami of non-communicable disease in the ageing global population. This ‘diseasome of ageing’ [ 1 , 2 ] reflects a range of ‘burden...
Articles
NRF2/ACSS2 axis mediates the metabolic effect of alcohol drinking on esophageal squamous cell carcinoma
Available to PurchaseJoab Otieno Odera, Zhaohui Xiong, Caizhi Huang, Ning Gu, Wenjun Yang, Jessie Githang'a, Elizabeth Odera, Chorlada Paiboonrungruang, Xiaoxin Chen
Journal:
Biochemical Journal
Biochem J (2020) 477 (16): 3075–3089.
Published: 28 August 2020
...-associated ESCC remain poorly understood. One of the most commonly mutated genes in ESCC is nuclear factor erythroid 2 like 2 ( NFE2L2 or NRF2 ), which is a critical transcription factor regulating oxidative stress response and drug detoxification. When NRF2 is hyperactive in cancer cells, however, it leads...
Includes: Supplementary data
Articles
Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2016) 473 (8): 961–1000.
Published: 08 April 2016
...Yiguo Zhang; Yuancai Xiang The consensus cis -regulatory AP-1 (activator protein-1)-like AREs (antioxidant-response elements) and/or EpREs (electrophile-response elements) allow for differential recruitment of Nrf1 [NF-E2 (nuclear factor-erythroid 2)-related factor 1], Nrf2 and Nrf3, together...
Articles
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
Available to PurchaseMingzhan Xue, Naila Rabbani, Hiroshi Momiji, Precious Imbasi, M. Maqsud Anwar, Neil Kitteringham, B. Kevin Park, Tomokazu Souma, Takashi Moriguchi, Masayuki Yamamoto, Paul J. Thornalley
Journal:
Biochemical Journal
Biochem J (2012) 443 (1): 213–222.
Published: 14 March 2012
... region of exon 1 of the mammalian Glo1 gene. Transcription factor Nrf2 (nuclear factor-erythroid 2 p45 subunit-related factor 2) binds to this ARE, increasing basal and inducible expression of Glo1. Activators of Nrf2 induced increased Glo1 mRNA, protein and activity. Increased expression of Glo1...
Includes: Supplementary data
Articles
Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2009) 422 (1): 171–180.
Published: 29 July 2009
...Aimee L. Eggler; Evan Small; Mark Hannink; Andrew D. Mesecar Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor that activates transcription of a battery of cytoprotective genes by binding to the ARE (antioxidant response element). Nrf2 is repressed by the cysteine-rich...
Articles
Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2003) 374 (2): 337–348.
Published: 01 September 2003
...Paul NIOI; Michael McMAHON; Ken ITOH; Masayuki YAMAMOTO; John D. HAYES NQO1 [NAD(P)H:quinone oxidoreductase 1] has an integral role in cellular responses to oxidative stress. The expression of NQO1 is up-regulated in the mouse following challenge with electrophilic chemicals, in an Nrf2 (NF-E2 p45...
