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Keywords: O-glycosylation
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Articles
Biochem J (2021) 478 (8): 1585–1603.
Published: 28 April 2021
...D. Judy Shon; Angel Kuo; Michael J. Ferracane; Stacy A. Malaker Epithelial surfaces throughout the body are coated by mucins, a class of proteins carrying domains characterized by a high density of O-glycosylated serine and threonine residues. The resulting mucosal layers form crucial host-microbe...
Articles
Biochem J (2018) 475 (9): 1583–1595.
Published: 09 May 2018
... lacking five O-glycosylation sites (Thr 134 /Thr 138 /Thr 143 /Thr 147 /Thr 152 ) in the threonine/proline-rich region increased cell adhesion activity and phosphorylation compared with the wild type. However, the role of O-glycosylation in cell adhesion activity and phosphorylation of OPN remains to be...
Includes: Supplementary data
Articles
Biochem J (2014) 463 (1): 93–102.
Published: 08 September 2014
... adhesion primarily through its association with several integrins such as αvβ3, and its phosphorylation affects these processes. However, the mechanism by which OPN O -glycosylation affects these processes is not completely understood. In the present study, we demonstrated that OPN O -glycosylation self...
Includes: Supplementary data
Articles
Biochem J (2008) 411 (1): 53–61.
Published: 13 March 2008
... alkaline phosphatase-conjugated secondary immunoglobulins. 27 7 2007 30 11 2007 12 12 2007 12 12 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 O-glycosylation osteopontin phosphorylation proteolytic processing sulfation uropontin...
Includes: Supplementary data
Articles
Biochem J (2006) 399 (1): 37–46.
Published: 13 September 2006
... 2006 The Biochemical Society, London 2006 ameloblast amelotin secretory calcium-binding phosphoprotein (SCPP) enamel organ junctional epithelium O-glycosylation Non-collagenous matrix proteins are minor constituents in calcified tissues, yet they play very important roles in...
Articles
Biochem J (2005) 390 (1): 285–292.
Published: 09 August 2005
... is a key molecule. 1 To whom correspondence should be addressed (email ess@imsb.au.dk ). 25 2 2005 21 4 2005 4 5 2005 4 5 2005 The Biochemical Society, London 2005 casein kinase II Golgi kinase mammary gland casein kinase O-glycosylation osteopontin...
Articles
Biochem J (2005) 388 (3): 731–740.
Published: 07 June 2005
... showing that ferritin is distributed non-randomly within the nuclear volume and that it preferentially associates with heterochromatin. Both cytoplasmic and nuclear populations of H-ferritin contain mixtures of non- and O-glycosylated forms, but the nuclear population is enriched in O-glycosylated forms...
Articles
Biochem J (2004) 382 (2): 501–510.
Published: 24 August 2004
...Teresa FREIRE; Cecilia FERNÁNDEZ; Cora CHALAR; Rick M. MAIZELS; Pedro ALZARI; Eduardo OSINAGA; Carlos ROBELLO As part of a general project aimed at elucidating the initiation of mucin-type O-glycosylation in helminth parasites, we have characterized a novel ppGalNAc-T (UDP- N -acetyl- D...
Articles
Biochem J (2003) 369 (3): 659–665.
Published: 01 February 2003
... are clustered around a 13 amino acid sequence that contains the main cleavage site for proteolytic processing of the subunit. Prevention of O-glycosylation by specific inhibitors leads to enhanced proteolytic processing and the consequence is an increased release of hmeprinβ into the culture medium...
Articles
Biochem J (2002) 367 (3): 609–616.
Published: 01 November 2002
... whom correspondence should be addressed (e-mail gunnar.hansson@medkem.gu.se ). 5 3 2002 28 6 2002 6 8 2002 7 8 2002 The Biochemical Society, London ©2002 2002 MS O-glycosylation Abbreviations used: ASL, airway surface liquid; CF, cystic fibrosis; CFTR, CF...
Articles
Biochem J (2001) 357 (1): 313–320.
Published: 25 June 2001
... Edman degradation, our study suggests that, in the O-glycosylation of mucin-type proteins, approach and recognition signalling by gp GaNTase-T7 and gp GaNTase-T9 depend largely on the peptide's primary structure (for example the presence of multiple clusters of hydroxy amino acids and the number of...
Articles
Biochem J (2001) 356 (1): 31–41.
Published: 08 May 2001
... STZ increases pancreatic islet O-linked protein glycosylation. In light of these data, we investigated the possibility further that STZ causes β-cell death by inhibiting O-GlcNAcase. In isolated islets, the time course and dose curve of STZ-induced O-glycosylation correlated with β-cell toxicity. STZ...
Articles
Biochem J (2001) 353 (1): 33–40.
Published: 18 December 2000
... containing approx. 5–10kDa of N-linked glycans. The precursor was gradually converted into a high-molecular-mass mature form, owing mainly, if not entirely, to O-glycosylation. The mature molecule consists of two major glycoforms that differ in sialylation. Unlike secreted mucins, epiglycanin did not form...
Articles
Biochem J (2000) 352 (1): 37–48.
Published: 07 November 2000
...@chouia.univ-lille1.fr ). 11 4 2000 5 7 2000 30 8 2000 The Biochemical Society, London © 2000 2000 O-glycosylation molecular cloning sialyltransferases Biochem. J. (2000) 352, 37 48 (Printed in Great Britain) 37 Cloning, expression and gene organization of a human Neu5Aca2...
Articles
Biochem J (2000) 350 (3): 805–814.
Published: 08 September 2000
..., London © 2000 2000 O-glycosylation mass spectrometry Muc2 parasite infection sialic acid Biochem. J. (2000) 350, 805 814 (Printed in Great Britain) 805 Identification of transient glycosylation alterations of sialylated mucin oligosaccharides during infection by the rat intestinal parasite...
Articles
Biochem J (2000) 350 (1): 109–114.
Published: 09 August 2000
...@endo.dom.uab.edu ). 11 2 2000 28 4 2000 23 5 2000 The Biochemical Society, London © 2000 2000 N-acetylglucosamine O-glycosylation transcription Biochem. J. (2000) 350, 109 114 (Printed in Great Britain) 109 Responsiveness of the state of O-linked N-acetylglucosamine modification...
Articles
Biochem J (2000) 347 (2): 535–542.
Published: 10 April 2000
...-tokyo.ac.jp). 6 9 1999 7 12 1999 11 2 2000 The Biochemical Society, London © 2000 2000 mucin O-glycosylation tumour antigen UDP-GalNAc:polypeptide N-acetyl-d-galactosaminyltransferase Biochem. J. (2000) 347, 535 542 (Printed in Great Britain) 535 Order and maximum...
Articles
Biochem J (1999) 344 (3): 775–786.
Published: 08 December 1999
... Society, London © 1999 1999 electron microscopy O-glycosylation phosphoserine Biochem. J. (1999) 344, 775 786 (Printed in Great Britain) 775 Proteophosphoglycans of Leishmania mexicana Identification, purification, structural and ultrastructural characterization of the secreted promastigote...
Articles
Biochem J (1999) 344 (3): 787–795.
Published: 08 December 1999
... AJ245667, AJ245668 and AJ245669. 24 6 1999 20 8 1999 10 9 1999 The Biochemical Society, London © 1999 1999 gene replacement O-glycosylation peptide repeats. Biochem. J. (1999) 344, 787 795 (Printed in Great Britain) 787 Proteophosphoglycans of Leishmania mexicana...
Articles
Biochem J (1999) 343 (3): 645–652.
Published: 25 October 1999
... combination of MS and Edman degradation. The heterogeneity in SP-D was caused mainly by a high number of post-translational modifications in the collagen-like region. Proline and lysine residues were partly hydroxylated and lysine residues were further O-glycosylated with the disaccharide galactose-glucose. A...
Articles
Biochem J (1999) 341 (2): 277–284.
Published: 08 July 1999
... corresponding human protein, a type-I integral membrane protein of 162 amino acids. Madin-Darby canine kidney cells transfected with the cDNA clone directed the cell-surface expression of a 36-kDa O-glycosylated sialoglycoprotein, gp36, and two minor isoforms of 28 and 70 kDa. gp36 has a broad tissue...