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Keywords: Opi1
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Articles
Basic features of cellular inositol metabolism as revealed by a newly developed LC-MS method
Open AccessXue Bessie Su, Valeria Fedeli, Guizhen Liu, Meike Marie Amma, Paraskevi Boulasiki, Jingyi Wang, Mariano Bizzarri, Henning Jacob Jessen, Dorothea Fiedler, Antonella Riccio, Adolfo Saiardi
Journal:
Biochemical Journal
Biochem J (2025) 482 (11): 675–690.
Published: 26 May 2025
... in the transcription repressor OPI1 knockout opi1 Δ and decreased when wildtype yeast is fed with exogenous inositol. The method also revealed a new layer of regulation that takes place when exogenous inositol is added to further boost endogenous inositol synthesis in opi1 Δ in a positive feedback loop. Analyses...
Includes: Supplementary data
