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Keywords: PCNA
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Biochem J (2020) 477 (14): 2655–2677.
Published: 29 July 2020
... is sequential ubiquitination of proliferating cell nuclear antigen (PCNA), a DNA clamp required for replication and DNA repair. DDT consists of two parallel pathways: error-prone DDT is mediated by PCNA monoubiquitination, which recruits translesion synthesis DNA polymerases to bypass lesions with decreased...
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