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Keywords: PCNA
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Articles

DNA-damage tolerance through PCNA ubiquitination and sumoylation

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Li Fan, Tonghui Bi, Linxiao Wang, Wei Xiao
Journal: Biochemical Journal
Biochem J (2020) 477 (14): 2655–2677.
https://doi.org/10.1042/BCJ20190579
Published: 29 July 2020
... is sequential ubiquitination of proliferating cell nuclear antigen (PCNA), a DNA clamp required for replication and DNA repair. DDT consists of two parallel pathways: error-prone DDT is mediated by PCNA monoubiquitination, which recruits translesion synthesis DNA polymerases to bypass lesions with decreased...
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Articles

Functional dissection of proliferating-cell nuclear antigens (1 and 2) in human malarial parasite Plasmodium falciparum: possible involvement in DNA replication and DNA damage response

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Pallabi Mitra, Khadija Banu, Abhijit S. Deshmukh, Naidu Subbarao, Suman Kumar Dhar
Journal: Biochemical Journal
Biochem J (2015) 470 (1): 115–129.
https://doi.org/10.1042/BJ20150452
Published: 06 August 2015
...Pallabi Mitra; Khadija Banu; Abhijit S. Deshmukh; Naidu Subbarao; Suman Kumar Dhar Eukaryotic PCNAs (proliferating-cell nuclear antigens) play diverse roles in nucleic acid metabolism in addition to DNA replication. Plasmodium falciparum , which causes human malaria, harbours two PCNA homologues...
View articletitled, Functional dissection of proliferating-cell nuclear antigens (1 and 2) in human malarial parasite Plasmodium falciparum: possible involvement in DNA replication and DNA damage response
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