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Keywords: PNP2
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Biochem J (2021) 478 (19): 3655–3670.
Published: 14 October 2021
..., the Schistosoma purine salvage pathway is an attractive target for the development of necessary and selective new drugs. In this study, the purine nucleotide phosphorylase II (PNP2), a new isoform of PNP1, was submitted to a high-throughput fragment-based hit discovery using a crystallographic screening strategy...