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1-4 of 4
Keywords: PPARγ
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Articles
Regulation of the metabolism of apolipoprotein M and sphingosine 1-phosphate by hepatic PPARγ activity
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (12): 2009–2024.
Published: 21 June 2018
...Makoto Kurano; Hitoshi Ikeda; Naoyuki Iso-O; Masumi Hara; Kazuhisa Tsukamoto; Yutaka Yatomi Apolipoprotein M (apoM) is a carrier and a modulator of sphingosine 1-phosphate (S1P), an important multifunctional bioactive lipid. Since peroxisome proliferator-activated receptor γ (PPARγ) is reportedly...
Includes: Supplementary data
Articles
Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPARγ/RXR and RAR/RXR: down-regulation of CYP27A1–LXRα signaling
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (3): 621–642.
Published: 09 February 2018
...) was also decreased in acLDL-loaded CES1KD macrophages, suggesting reduced signaling through PPARγ–CYP27A1–LXRα. Consistent with this, treatment of CES1KD macrophages with agonists for PPARγ, RAR, and/or RAR/RXR partially restored transcription of CYP27A1 and LXRα , and repaired cholesterol influx...
Includes: Supplementary data
Articles
Bioenergetic programming of macrophages by the apolipoprotein A-I mimetic peptide 4F
Available to PurchaseGeeta Datta, Philip A. Kramer, Michelle S. Johnson, Hirotaka Sawada, Lesley E. Smythies, David K. Crossman, Balu Chacko, Scott W. Ballinger, David G. Westbrook, Palgunachari Mayakonda, G. M. Anantharamaiah, Victor M. Darley-Usmar, C. Roger White
Journal:
Biochemical Journal
Biochem J (2015) 467 (3): 517–527.
Published: 17 April 2015
... in MDMs that play an important role in lipid metabolism, including PPARγ (peroxisome-proliferator-activated receptor γ) and CD36. Addition of 4F was associated with a significant increase in FA (fatty acid) uptake and oxidation compared with vehicle treatment. Mitochondrial respiration was assessed...
Articles
Decreased adipogenesis and adipose tissue in mice with inactivated protein phosphatase 5
Open Access
Journal:
Biochemical Journal
Biochem J (2015) 466 (1): 163–176.
Published: 06 February 2015
... proteins in the pathway of adipogenesis. glucocorticoid receptor Hsp90 PP5 preadipocyte differentiation preadipocyte factor-1 PPARγ Mutation of Asp274 to Ala in Ppp5 would be predicted to lead to inactivation because this amino acid is invariant throughout the PPP family phosphatases...
Includes: Supplementary data
