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Keywords: PTEN
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Biochem J (2021) 478 (14): 2899–2920.
Published: 28 July 2021
... 2021 DUSP6 PP2A PTEN PTP1B SHP2 WIP1 In normal adult tissues, stem cells (SCs) confer the capacity for tissue regeneration and homeostasis [ 1 ]. The self-renewal capacity of SCs, and generation of differentiated cellular progenies, is a prerequisite for tissue maintenance and repair...
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Biochem J (2019) 476 (1): 1–23.
Published: 07 January 2019
... phosphoinositide 3-kinase PTEN transmembrane proteins PPIs (polyphosphoinositides) are reversibly phosphorylated derivatives of the membrane phospholipid phosphatidylinositol (PI, Figure 1A ). They are low-abundance lipids of the cytoplasmic leaflet of all eukaryotic cellular membranes. PPIs...
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Biochem J (2005) 390 (2): 613–623.
Published: 23 August 2005
...Isabel Rodríguez-Escudero; Françoise M. Roelants; Jeremy Thorner; César Nombela; María Molina; Víctor J. Cid The mammalian signalling pathway involving class I PI3K (phosphoinositide 3-kinase), PTEN (phosphatidylinositol 3-phosphatase) and PKB (protein kinase B)/c-Akt has roles in multiple...
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Biochem J (2001) 360 (2): 277–283.
Published: 26 November 2001
...Steven M. WALKER; C. Peter DOWNES; Nick R. LESLIE The PTEN (phosphatase and tensin homologue deleted on chromosome 10) tumour suppressor is a phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5) P 3 ] 3-phosphatase that plays a critical role in regulating many cellular processes by antagonizing...