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Keywords: RecQ
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Articles

RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin

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Furqan Sami, Xing Lu, Swetha Parvathaneni, Rabindra Roy, Ronald K. Gary, Sudha Sharma
Journal: Biochemical Journal
Biochem J (2015) 468 (2): 227–244.
https://doi.org/10.1042/BJ20141021
Published: 22 May 2015
...Furqan Sami; Xing Lu; Swetha Parvathaneni; Rabindra Roy; Ronald K. Gary; Sudha Sharma RecQ helicases are a family of highly conserved proteins that maintain genomic stability through their important roles in replication restart mechanisms. Cellular phenotypes of RECQ1 deficiency are indicative...
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Includes: Supplementary data
Articles

Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability

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Sudha Sharma, Kevin M. Doherty, Robert M. Brosh, Jr
Journal: Biochemical Journal
Biochem J (2006) 398 (3): 319–337.
https://doi.org/10.1042/BJ20060450
Published: 29 August 2006
... for the maintenance of genome stability. In particular, mutations in genes of the RecQ family of DNA helicases result in chromosomal instability diseases of premature aging and/or cancer predisposition. We will discuss the mechanisms of RecQ helicases in pathways of DNA metabolism. A review of RecQ helicases from...
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