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Keywords: RhoGTPase
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Biochem J (2013) 455 (2): 251–260.
Published: 27 September 2013
...Ligia I. Bastea; Heike Döppler; Sarah E. Pearce; Nisha Durand; Samantha J. Spratley; Peter Storz PAKs (p21-activated kinases) are effectors of RhoGTPases. PAK4 contributes to regulation of cofilin at the leading edge of migrating cells through activation of LIMK (Lin-11/Isl-1/Mec-3 kinase). PAK4...
Includes: Supplementary data
Biochem J (2012) 442 (1): 13–25.
Published: 27 January 2012
... Society 2012 adhesion E3 ligase integrin migration RhoGTPase ubiquitin The complexity of protein ubiquitylation and the machinery that regulates it is mind-boggling ( Figure 1 ). Mammalian cells express two E1 ligases and approximately 30 E2 ligases in addition to over 600 potential E3...