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Keywords: S100 proteins
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Biochem J (2016) 473 (1): 31–42.
Published: 09 December 2015
... and include matrix remodelling, adhesion and migration. S100A4 belongs to the Ca 2+ -binding EF-hand S100 protein family and acts both intra- and extra-cellularly through binding to various partners. It regulates cell migration and its overexpression is strongly associated with metastasis and poor survival...