...Min Du; Guozheng Wang; Igor L. Barsukov; Stephane R. Gross; Richard Smith; Philip S. Rudland Overexpression of S100P promotes breast cancer metastasis in animals and elevated levels in primary breast cancers are associated with poor patient outcomes. S100P can differentially interact with nonmuscle...

...Christopher J. Clarke; Stephane R. Gross; Thamir M. Ismail; Philip S. Rudland; Morteta Al-Medhtiy; Michael Santangeli; Roger Barraclough S100P protein in human breast cancer cells is associated with reduced patient survival and, in a model system of metastasis, it confers a metastatic phenotype...

... significance is unknown. In the present study, S100A1 was found to interact with another S100 protein, S100P, by using the yeast two-hybrid system. The binding parameters of the interaction were obtained using an optical biosensor and show that S100P has a slightly higher affinity for S100A1 ( K d =10–20 nM...