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Keywords: S23906-1
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Biochem J (2013) 452 (1): 147–159.
Published: 25 April 2013
... S23906-1 alkylates guanine nucleobases in the minor groove of the DNA helix and presents an original ability to locally open the double helix of DNA, which appears to be associated with its cytotoxic activity. However, the molecular mechanism linking adduct formation to cellular consequences is not...
Includes: Supplementary data