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Keywords: SARS-CoV E protein
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Coronavirus
Yu Yang, Zeyu Xiong, Sheng Zhang, Yan Yan, Justin Nguyen, Bernard Ng, Huifang Lu, John Brendese, Fan Yang, Hong Wang, Xiao-Feng Yang
Journal:
Biochemical Journal
Biochem J (2005) 392 (1): 135–143.
Published: 08 November 2005
... that is homologous with MHV E protein, thus inducing T-cell apoptosis. To test this hypothesis, a cDNA encoding SARS-CoV E protein was created using whole gene synthesis. Our results showed that SARS-CoV E protein induced apoptosis in the transfected Jurkat T-cells, which was amplified to higher apoptosis rates...