... the secretory pathway, many aspects concerning the control of this process are not yet fully understood. α-Taxilin was identified as a novel binding partner of syntaxin-4 and of other members of the syntaxin family, which are part of SNARE (soluble N -ethylmaleimide-sensitive fusion protein-attachment protein...

...-triggered membrane fusion. After fusion, the membrane around the secretory vesicle is incorporated into the plasma membrane and the granule releases its contents. The proteins involved in these processes belong to several highly conserved families: Rab GTPases, SNAREs (soluble NSF-attachment protein...

... is a substrate for S-nitrosylation and that NO disrupts the binding of Munc18-1 to the closed conformation of syntaxin 1a in vitro . In contrast, NO does not inhibit SNARE {SNAP [soluble NSF ( N -ethylmaleimide-sensitive fusion protein) attachment protein] receptor} complex formation or binding of Munc18-1...

... homology domain; Q-SNARE, glutamine-containing SNARE; Rab5ip, Rab5-interacting protein ; RILP, Rab-interacting lysosomal protein ; R-SNARE, arginine-containing SNARE; SNAP, NSF-attachment protein ; SNARE, soluble NSF-attachment protein receptor ; TfR, transferrin receptor ; VAMP, vesicle-associated...

...Lee P. HAYNES; Alan MORGAN; Robert D. BURGOYNE The target-SNARE syntaxin 1A is an essential component of the core machinery required for regulated exocytosis (where SNARE is the soluble N -ethylmaleimide-sensitive fusion protein-attachment protein receptor). Syntaxin 1A interacts with a variety...

... 1999 exocytosis islet neurotoxin regulated release SNARE Biochem. J. (1999) 339, 159 165 (Printed in Great Britain) 159 SNAP-25a and -25b isoforms are both expressed in insulin-secreting cells and can function in insulin secretion Carmen GONELLE-GISPERT*, Philippe A. HALBAN*, Heiner NIEMANN...