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Keywords: Scribble
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Biochem J (2021) 478 (7): 1321–1332.
Published: 06 April 2021
...Jing Yuan How; Rebecca K. Stephens; Krystle Y.B. Lim; Patrick O. Humbert; Marc Kvansakul Scribble is a critical cell polarity regulator that has been shown to work as either an oncogene or tumor suppressor in a context dependent manner, and also impacts cell migration, tissue architecture and...
Includes: Supplementary data
Biochem J (2015) 468 (1): 133–144.
Published: 05 May 2015
... study, we found that the two PDZ domains within the PDZ34 tandem of Scribble, a cell polarity regulator, tightly pack in a ‘front-to-back’ mode to form a compact supramodule. Although PDZ4 contains a distorted αB/βB pocket, the attachment of PDZ4 to PDZ3 generates an unexpected interdomain pocket that...
Includes: Supplementary data