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Keywords: Shigella sonnei
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Articles
Expression of different bacterial cytotoxins is controlled by two global transcription factors, CRP and Fis, that co-operate in a shared-recruitment mechanism
Available to PurchaseAmanda E. Rossiter, Rita E. Godfrey, Jack A. Connolly, Stephen J. W. Busby, Ian R. Henderson, Douglas F. Browning
Journal:
Biochemical Journal
Biochem J (2015) 466 (2): 323–335.
Published: 20 February 2015
... and requires Fis to bind upstream to promote full activation. Here, we show that CRP and Fis control the expression of other important autotransporter toxins, namely Sat from uropathogenic E. coli (UPEC) and SigA from Shigella sonnei , and that this regulation has been conserved in different pathogens...
Includes: Supplementary data