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Keywords: Smad1
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Biochem J (2011) 433 (2): 333–343.
Published: 22 December 2010
... (extracellular-signal-regulated kinase 1/2) pathway, which is required for senescence, was not activated by BMP4 in the lung cancer cell line NCI-H460. We also showed that the BMP4-responsive R-Smads (receptor-regulated Smads), i.e. Smad1 and Smad5, were necessary for the up-regulation of p16 INK4a and p21 WAF1...
Includes: Supplementary data