1-4 of 4
Keywords: Smad3
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression

Available to Purchase
Anindita Dutta, Jing Li, Carmine Fedele, Aejaz Sayeed, Amrita Singh, Shelia M. Violette, Thomas D. Manes, Lucia R. Languino
Journal: Biochemical Journal
Biochem J (2015) 466 (3): 525–536.
https://doi.org/10.1042/BJ20140698
Published: 06 March 2015
...Anindita Dutta; Jing Li; Carmine Fedele; Aejaz Sayeed; Amrita Singh; Shelia M. Violette; Thomas D. Manes; Lucia R. Languino The present study establishes that the avβ6 integrin associates with the transforming growth factor (TGF)β receptor (TβR) and is required for the activation of the TGFβ–Smad3...
View articletitled, αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression
Open the PDF for αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression in another window
Articles

Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-β-mediated cancer cell invasiveness

Available to Purchase
Isao Matsuura, Chen-Yu Lai, Keng-Nan Chiang
Journal: Biochemical Journal
Biochem J (2010) 426 (3): 327–335.
https://doi.org/10.1042/BJ20090990
Published: 24 February 2010
..., a metastasis-associated protein, also called metastatin-1, can physically and functionally interact with Smad3, an important mediator of TGF-β signalling. In agreement with its known property, S100A4 binds to Smad3 in a Ca 2+ -dependent manner. The S100A4-binding site is located in the N-terminal region...
View articletitled, Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-β-mediated cancer cell invasiveness
Open the PDF for Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-β-mediated cancer cell invasiveness in another window
Articles

The essential role for c-Ski in mediating TGF-β1-induced bi-directional effects on skin fibroblast proliferation through a feedback loop

Available to Purchase
Xia Liu, Ping Li, Ping Liu, Renping Xiong, En Zhang, Xingyun Chen, Dayong Gu, Yan Zhao, Zhengguo Wang, Yuanguo Zhou
Journal: Biochemical Journal
Biochem J (2008) 409 (1): 289–297.
https://doi.org/10.1042/BJ20070545
Published: 11 December 2007
... important significance during tissue repair. The mechanism has not been defined. c-Ski is a major co-repressor of TGF-β1/Smad3 signalling; however, the exact role of c-Ski in the bi-directional regulation of fibroblast proliferation remains to be determined. In the present study, we established a dose...
View articletitled, The essential role for c-Ski in mediating TGF-β1-induced bi-directional effects on skin fibroblast proliferation through a feedback loop
Open the PDF for The essential role for c-Ski in mediating TGF-β1-induced bi-directional effects on skin fibroblast proliferation through a feedback loop in another window
Includes: Supplementary data
Articles

The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFβ1 responses in human proximal-tubule epithelial cells

Available to Purchase
Mysore K. Phanish, Nadia A. Wahab, Paul Colville-Nash, Bruce M. Hendry, Mark E. C. Dockrell
Journal: Biochemical Journal
Biochem J (2006) 393 (2): 601–607.
https://doi.org/10.1042/BJ20051106
Published: 23 December 2005
... events in the development of tubulo-interstitial fibrosis. In the present study we have investigated the distinct contributions of Smad2 and Smad3 to expression of CTGF, E-cadherin, α-SMA (α-smooth-muscle actin) and MMP-2 (matrix-metalloproteinase-2) in response to TGFβ1 treatment in an in vitro culture...
View articletitled, The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFβ1 responses in human proximal-tubule epithelial cells
Open the PDF for The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFβ1 responses in human proximal-tubule epithelial cells in another window