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Keywords: Snail
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Articles

Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression

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Mario A. Shields, Surabhi Dangi-Garimella, Amanda J. Redig, Hidayatullah G. Munshi
Journal: Biochemical Journal
Biochem J (2012) 441 (2): 541–552.
https://doi.org/10.1042/BJ20111240
Published: 21 December 2011
... 30 8 2011 5 9 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 chemoresistance fibrosis microRNA membrane-type 1 matrix metalloproteinase (MT1-MMP) pancreatic cancer Snail transforming growth factor-β (TGF-β) In the complex interplay between...
View articletitled, Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression
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Includes: Multimedia, Supplementary data
Articles

Transforming growth factor-β2 promotes Snail-mediated endothelial–mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling

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Damian Medici, Scott Potenta, Raghu Kalluri
Journal: Biochemical Journal
Biochem J (2011) 437 (3): 515–520.
https://doi.org/10.1042/BJ20101500
Published: 13 July 2011
...-induced EndMT. Furthermore, we show that all of these pathways are essential for increasing expression of the cell-adhesion-suppressing transcription factor Snail. Inhibition of Snail with siRNA (small interfering RNA) prevents TGF-β2-induced EndMT. However, overexpression of Snail is not sufficient...
View articletitled, Transforming growth factor-β2 promotes Snail-mediated endothelial–mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling
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Articles

The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells

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Ofelia M. Martínez-Estrada, Albert Cullerés, Francesc X. Soriano, Hector Peinado, Victoria Bolós, Fernando O. Martínez, Manuel Reina, Amparo Cano, Myriam Fabre, Senén Vilaró
Journal: Biochemical Journal
Biochem J (2006) 394 (2): 449–457.
https://doi.org/10.1042/BJ20050591
Published: 10 February 2006
...Ofelia M. Martínez-Estrada; Albert Cullerés; Francesc X. Soriano; Hector Peinado; Victoria Bolós; Fernando O. Martínez; Manuel Reina; Amparo Cano; Myriam Fabre; Senén Vilaró Claudin-1 is an integral membrane protein component of tight junctions. The Snail family of transcription factors...
View articletitled, The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells
Open the PDF for The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells in another window
Includes: Supplementary data