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Keywords: TNF-
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Articles
Regulation of interleukin-6 gene expression by pro-inflammatory cytokines in a colon cancer cell line
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2000) 349 (3): 765–773.
Published: 25 July 2000
... high levels of IL-6 in response to tumour necrosis factor-α (TNF-α) and IL-1β, the HTM-29 cell line failed to produce both IL-6 protein and mRNA. Nevertheless, the transcription factors nuclear factor-κB (NF-κB) and NF-IL6, the main factors involved in IL-6 gene transcriptional activation by cytokines...
