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Keywords: Trypanosoma brucei
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Biochem J (2019) 476 (2): 179–191.
Published: 18 January 2019
... Commons Attribution License 4.0 (CC BY) . human Leishmania phosphofructokinase reverse reaction Trypanosoma cruzi Trypanosoma brucei Phosphofructokinase (PFK) catalyses the phosphorylation of fructose 6-phosphate (F6P) to fructose 1,6-bisphosphate (F1,6BP) and plays a central role...
Includes: Supplementary data
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Biochem J (2010) 425 (3): 603–614.
Published: 15 January 2010
...Helen Denton; Stewart Fyffe; Terry K. Smith A putative GDP-Man PP (guanidine diphosphomannose pyrophosphorylase) gene from Trypanosoma brucei ( Tb GDP-Man PP) was identified in the genome and subsequently cloned, sequenced and recombinantly expressed, and shown to be a catalytically active dimer...
Includes: Supplementary data
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Biochem J (2009) 417 (3): 685–694.
Published: 16 January 2009
...Sandesh Subramanya; C. Frank Hardin; Dietmar Steverding; Kojo Mensa-Wilmot GPI-PLC (glycosylphosphatidylinositol-specific phospholipase C) is expressed in bloodstream-form Trypanosoma brucei , a protozoan that causes human African trypanosomiasis. Loss of genes encoding GPI-PLC reduces...
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Biochem J (2008) 409 (2): 563–569.
Published: 21 December 2007
... to treat patients with late-stage African trypanosomiasis, the requirement for additional drug targets is paramount. Here, we report the biochemical properties of TbSpSyn ( Trypanosoma brucei spermidine synthase), the enzyme immediately downstream of ODC in this pathway. Recombinant TbSpSyn was purified...
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Biochem J (2007) 402 (1): 43–49.
Published: 25 January 2007
... trypanosomes possess two isoforms that are localized in the cytosol and in the mitochondrion of the parasites respectively. Here we report on the biological significance of the cTXN (cytosolic TXN) of Trypanosoma brucei for hydroperoxide detoxification. Depending on the growth phase, the concentration...
Includes: Supplementary data
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