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Keywords: ULK kinase
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Sebastian Mathea, Eidarus Salah, Cynthia Tallant, Deep Chatterjee, Benedict-Tilman Berger, Rebecca Konietzny, Susanne Müller, Benedikt M. Kessler, Stefan Knapp
Journal:
Biochemical Journal
Biochem J (2021) 478 (14): 2811–2823.
Published: 23 July 2021
..., we present the first high-resolution structures of the ULK3 kinase domain. Its unique features are explored against the background of other ULK kinases. An inhibitor fingerprint indicates that ULK3 is highly druggable and capable of adopting a wide range of conformations. In accordance with this, we...
Includes: Supplementary data