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Keywords: ULK2
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In Collection
Editors' pick of research highlights published in the Biochemical Journal in 2018 & 2019
Apirat Chaikuad, Sebastian E. Koschade, Alexandra Stolz, Katarina Zivkovic, Christian Pohl, Shabnam Shaid, Huiyu Ren, Lester J. Lambert, Nicholas D.P. Cosford, Christian H. Brandts, Stefan Knapp
Journal:
Biochemical Journal
Biochem J (2019) 476 (5): 875–887.
Published: 12 March 2019
... related kinase ULK2 (Unc-51-like autophagy activating kinase 2). Here, we present the crystal structure of ULK2 in complex with ATP competitive inhibitors. Surprisingly, the ULK2 structure revealed a dimeric assembly reminiscent of dimeric arrangements of auto-activating kinases suggesting a role...
Includes: Supplementary data
