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Keywords: UPR
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Articles
Olaya Yassin, Bellam Praveen, Odai Darawshi, Thomas LaFramboise, Miriam Shmuel, Shakti P. Pattanayak, Brian K. Law, Maria Hatzoglou, Boaz Tirosh
Journal:
Biochemical Journal
Biochem J (2024) 481 (24): 1921–1935.
Published: 09 December 2024
... disulfides ER stress trafficking UPR Protein folding in the endoplasmic reticulum (ER) is dependent on post translational modifications unique to the ER, such as N-linked glycosylation and disulfide bond formation. When impaired, proteins folding is impeded, and conditions of ER stress develop...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2015) 468 (1): 33–47.
Published: 05 May 2015
...-essential mutants in the regulatory subunits of Glc7 revealed that the lack of Reg1, and no other subunit, causes hypersensitivity to unfolded protein response (UPR)-inducers, which was concomitant with an augmented UPR element-dependent transcriptional response. The Glc7–Reg1 complex takes part...
Includes: Supplementary data