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Keywords: Vangl2
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Biochem J (2021) 478 (7): 1321–1332.
Published: 06 April 2021
... immunity. Mutations in Scribble lead to neural tube defects in mice and humans, which has been attributed to a loss of interaction with the planar cell polarity regulator Vangl2. We show that the Scribble PDZ domains 1, 2 and 3 are able to interact with the C-terminal PDZ binding motif of Vangl2 and have...
Includes: Supplementary data