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Keywords: Wnt target genes
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Cheril Tapia-Rojas, Andreas Schüller, Carolina B. Lindsay, Roxana C. Ureta, Cristóbal Mejías-Reyes, Juan Hancke, Francisco Melo, Nibaldo C. Inestrosa
Journal:
Biochemical Journal
Biochem J (2015) 466 (2): 415–430.
Published: 20 February 2015
... of Wnt target genes by a mechanism that bypasses Wnt ligand binding to its receptor. In vitro kinase assays demonstrate that ANDRO inhibits glycogen synthase kinase (GSK)-3β by a non-ATP-competitive, substrate-competitive mode of action. In silico analyses suggest that ANDRO interacts with the substrate...
Includes: Supplementary data
