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Keywords: acetyl-CoA carboxylase
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Articles
Journal:
Biochemical Journal
Biochem J (2017) 474 (22): 3783–3797.
Published: 06 November 2017
..., Finland. ACC1 acetyl-CoA carboxylase ACSF3 malonyl-CoA mitochondrial fatty acid synthesis mitochondrial biogenesis 24 5 2017 29 9 2017 3 10 2017 6 10 2017 © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2017...
Includes: Supplementary data
Articles
Rebecca J. Ford, Morgan D. Fullerton, Stephen L. Pinkosky, Emily A. Day, John W. Scott, Jonathan S. Oakhill, Adam L. Bujak, Brennan K. Smith, Justin D. Crane, Regje M. Blümer, Katarina Marcinko, Bruce E. Kemp, Hertzel C. Gerstein, Gregory R. Steinberg
Journal:
Biochemical Journal
Biochem J (2015) 468 (1): 125–132.
Published: 05 May 2015
... interacting directly at the AMPK β1 drug-binding site. AMPK activation by both drugs results in phosphorylation of ACC (acetyl-CoA carboxylase; P-ACC) and inhibition of acetyl-CoA carboxylase (ACC), the rate limiting enzyme controlling fatty acid synthesis (lipogenesis). We find doses of metformin...
Articles
Journal:
Biochemical Journal
Biochem J (2005) 392 (1): 201–209.
Published: 08 November 2005
... by switching off ATP-consuming pathways and switching on ATP-generating pathways when ATP is limiting. AMPK was first discovered as an activity that inhibited preparations of ACC1 (acetyl-CoA carboxylase), a regulator of cellular fatty acid synthesis. We report that NM23-H1/NDPK A and AMPK α1 are associated...
Articles
Journal:
Biochemical Journal
Biochem J (2004) 380 (1): 105–110.
Published: 15 May 2004
...Stephanie C. WEATHERLY; Sandra L. VOLRATH; Tedd D. ELICH Acetyl-CoA carboxylase (ACC) catalyses the first step in fatty-acid biosynthesis. Owing to its role in primary metabolism, ACC has been exploited as a commercial herbicide target and identified as a chemically validated fungicide target...
Articles
Journal:
Biochemical Journal
Biochem J (2003) 375 (2): 415–423.
Published: 15 October 2003
...Lindsey J. PRICE; Derek HERBERT; Stephen R. MOSS; David J. COLE; John L. HARWOOD The sensitivity of grass species to important classes of graminicide herbicides inhibiting ACCase (acetyl-CoA carboxylase) is associated with a specific inhibition of the multifunctional ACCase located in the plastids...