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Keywords: acetyl-CoA carboxylase (ACC)
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Articles
Andrew J. O’Brien, Linda A. Villani, Lindsay A. Broadfield, Vanessa P. Houde, Sandra Galic, Giovanni Blandino, Bruce E. Kemp, Theodoros Tsakiridis, Paola Muti, Gregory R. Steinberg
Journal:
Biochemical Journal
Biochem J (2015) 469 (2): 177–187.
Published: 06 July 2015
... charge of the cell. A hallmark of many cancers is high rates of fatty acid synthesis and AMPK inhibits this pathway through phosphorylation of acetyl-CoA carboxylase (ACC). It is currently unknown whether targeting the AMPK–ACC-lipogenic pathway using salicylate and/or metformin may be effective...
Articles
Yu-Chiang Lai, Samanta Kviklyte, Didier Vertommen, Louise Lantier, Marc Foretz, Benoît Viollet, Stefan Hallén, Mark H. Rider
Journal:
Biochemical Journal
Biochem J (2014) 460 (3): 363–375.
Published: 29 May 2014
... 25 3 2014 25 3 2014 AMP-activated protein kinase activator (AMPK activator) acetyl-CoA carboxylase (ACC) fatty acid oxidation glycogen protein synthesis Rat epitrochlearis and mouse EDL (extensor digitorum longus) and soleus muscles were incubated as described in [ 36 , 37...
Includes: Supplementary data
Articles
Dongju Jung, Lutfi Abu-Elheiga, Rie Ayuzawa, Ziwei Gu, Takashi Shirakawa, Yukio Fujiki, Norio Nakatsuji, Salih J. Wakil, Motonari Uesugi
Journal:
Biochemical Journal
Biochem J (2012) 448 (3): 409–416.
Published: 21 November 2012
... compilation © 2012 Biochemical Society 2012 acetyl-CoA carboxylase (ACC) adipogenesis chromeceptin malonyl-CoA multifunctional protein 2 (MFP-2) peroxisomal translocation ACCs (acetyl-CoA carboxylases, EC 6.4.1.2.) are biotin-containing enzymes involved in fatty acid biosynthesis...
Includes: Supplementary data