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Keywords: acidic domain
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Biochem J (2002) 367 (1): 229–238.
Published: 01 October 2002
... of the other members of the M16 family of metalloendopeptidases by a 90 amino acid acidic domain (DAC) inserted close to its active site. At the cell surface, NRDc binds heparin-binding epidermal growth factor-like growth factor (HB-EGF) and enhances HB-EGF-induced cell migration. An active-site...