...–mesenchymal transition) that occurs during normal development and malignant progression is a typical example of the phenotypic switch associated with profound actin remodelling and changes in gene expression. For instance, actin dynamics control motile cell functions in EMT, in part, through regulating...

[email protected] ). actin depolymerizing factor (ADF)/cofilin actin dynamics cyclase-associated protein (CAP) depolymerization nucleotide exchange polymerization Modulation of actin filament turnover is critical for many cell biological events. Actin by itself can undergo turnover or treadmilling...

... assay, suggesting that lamellipodial persistence as seen in two-dimensions is not crucial in three-dimensional environments. actin dynamics breast cancer cell invasion lamellipodium migration Scar/WAVE complex The mammalian Scar (suppressor of cAMP receptor)/WAVE [WASP (Wiskott–Aldrich...

...Keiko Kawauchi; Wee Wee Tan; Keigo Araki; Farhana Binte Abu Bakar; Minsoo Kim; Hideaki Fujita; Hiroaki Hirata; Yasuhiro Sawada Actin dynamics are implicated in various cellular processes, not only through the regulation of cytoskeletal organization, but also via the control of gene expression...

...Elisa M. Nevalainen; Aneta Skwarek-Maruszewska; Attila Braun; Markus Moser; Pekka Lappalainen Twf (twinfilin) is an evolutionarily conserved regulator of actin dynamics composed of two ADF-H (actin-depolymerizing factor homology) domains. Twf binds actin monomers and heterodimeric capping protein...

... actin dynamics glucose transporter 4 (GLUT4) insulin signalling muscle cells phosphoinositide vesicle traffic Finally, we focus the present review on studies in both muscle and fat cells. Of note, human and rodent skeletal muscle or muscle cells respond to insulin with a 2- to 3-fold gain...

...Rosaria COSTA; Derek T. WARREN; Kathryn R. AYSCOUGH The importance of coupling the process of endocytosis to factors that regulate actin dynamics has been clearly demonstrated in yeast, and many proteins involved in these mechanisms have been identified. Sla1p is a well-characterized yeast protein...