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Keywords: acute myeloid leukaemia
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Articles

Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia

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Anil Kumar Singh, Vishal Upadhyay, Arppita Sethi, Sangita Chowdhury, Shivkant Mishra, Shailendra Prasad Verma, Madan Lal Brahma Bhatt, Arun Kumar Trivedi
Journal: Biochemical Journal
Biochem J (2024) 481 (10): 653–666.
https://doi.org/10.1042/BCJ20240027
Published: 10 May 2024
... myeloid leukaemia C/EBPα differentiation RNF138 ubiquitin ligases ubiquitination Acute myeloid leukemia (AML) is a hematological malignancy characterized by the abnormal accumulation and uncontrolled proliferation of immature progenitor cells in the bone marrow and peripheral blood of AML...
View articletitled, Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia
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Includes: Supplementary data
Articles

hnRNP K in PU.1-containing complexes recruited at the CD11b promoter: a distinct role in modulating granulocytic and monocytic differentiation of AML-derived cells

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Ervin Nika, Federica Brugnoli, Manuela Piazzi, Elisabetta Lambertini, Silvia Grassilli, Alberto Bavelloni, Roberta Piva, Silvano Capitani, Valeria Bertagnolo
Journal: Biochemical Journal
Biochem J (2014) 463 (1): 115–122.
https://doi.org/10.1042/BJ20140358
Published: 08 September 2014
... forms on the CD11b promoter during the agonist-induced maturation of AML (acute myeloid leukaemia)-derived cells along both the granulocytic and the monocytic lineages. Although hnRNP K and PU.1 act synergistically during granulocytic differentiation, hnRNP K seems to have a negative effect on PU.1...
View articletitled, hnRNP K in PU.1-containing complexes recruited at the CD11b promoter: a distinct role in modulating granulocytic and monocytic differentiation of AML-derived cells
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Articles

Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1

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Christian Ries, Thomas Pitsch, Reinhard Mentele, Stefan Zahler, Virginia Egea, Hideaki Nagase, Marianne Jochum
Journal: Biochemical Journal
Biochem J (2007) 405 (3): 547–558.
https://doi.org/10.1042/BJ20070191
Published: 13 July 2007
...) were used. The developed films were scanned and analysed using the ImageMaster-1D Elite software. acute myeloid leukaemia gelatinase B glycosylation matrix metalloproteinase (MMP) tissue inhibitor of metalloproteinase (TIMP) tumour cell invasion MMPs (matrix metalloproteinases...
View articletitled, Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1
Open the PDF for Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1 in another window